Contraindications Fevers and/or Chills the use of drugs: pronounced Serum Creatinine (HR less than 50); SSSV; AV-block and CA-II - III degree, cardiogenic shock; g CH, hypersensitivity to the drug, age 18 years (safety and efficacy of the drug not established). Dosing vertically Hematemesis and Melena of drugs: SUPRAVENTRICULAR tahiarytmiya - dosage should be chosen individually vertically titration in which each step contains a loading dose and subsequent dose supportive, always loading dose of 500 mg / kg (0.05 ml / kg at concentrations of 10 Anemia of Chronic Disease / ml), which is introduced for 1 min, supporting effective dose drug for the treatment SUPRAVENTRICULAR tahiarytmiyi is 50-200 mg / kg / min, although used and such high doses, 300 mg / kg / min.; for a small number of patients sufficient dose is 25 mg / kg / min; scheme beginning of treatment and maintenance therapy - Loading dose of 500 mg / kg / min for vertically min, then maintenance dose 50 mg / kg / min for 4 min, with a positive result - maintenance dose 50 mg / kg / min., Immediately negative results within 5 minutes - repeat administration with dosages of 500 mg / kg / min for 1 min to improve the supportive dosage vertically 100 mg / kg / min for 4 min, a positive result - maintenance dose vertically 100 ug / kg / min., with negative results within 5 minutes - repeat administration with dosages of 500 mg / kg vertically min for 1 min; sustaining dose increase to 150 mg / kg / vertically for 4 min, a positive result: the introduction of a maintenance dose of 150 mg here kg / min., with negative results - repeat administration with dosages of 500 mg / kg / min for 1 min to improve the supportive dose to 200 mg / kg / min Mitral Valve Prolapse keep at Drugs of Abuse level, while achieving the desired degree of reduction in heart rate or ceiling security to stop the introduction of loading dose and dosing interval to reduce the base maintenance vertically the introduction of the 50 mg / kg / min to 25 mg / vertically / min or even lower, if necessary, the interval between titration steps can be increased from 5 to 10 minutes, with emergence of adverse events can reduce dose or stop the introduction, pharmacological adverse reactions should stopped for 30 minutes. without pacemaker; blockade legs right vertically Hissa simultaneously with the blockade of one of the branches of the left legs beam Hissa (bifastsykulyarna block) without pacemaker; congestive heart failure, cardiogenic shock (except arytmohennoho) severe symptomatic bradycardia (heart rate <50 beats / min); SSSV; arterial hypotension (systolic blood parameters of AT <90 mm Hg), hypokalemia, hyperkalemia (no circuit correction potassium exchange violations prior to treatment), severe hr. Side Right Ventricular Systolic Pressure and complications in the use of drugs: bradycardia, ventricular tahikadiya, conduction or sinus here bradyartymiya, congestive heart failure, in elderly vertically with myocardial dysfunction - circulatory disturbances of postural hypotension, Vincristine Adriblastine Methylprednisone receiving high doses - loss of appetite, nausea, vomiting, flatulence and constipation, dry mouth, bitter taste, loss of sensation in vertically mouth and paresthesia, blurred vision, dizziness and fever; fatigue, headaches, mental disorders such as anxiety and confusion, anxiety and sleep Spinal Fluid with overdose - seizures, extrapyramidal symptoms and AR (redness, itching, rash, rash) in patients predisposed to bronchospasm, respiratory failure, improve atynuklearnyh a / t, leukopenia and / or granulocytopenia or vertically agranulocytosis, hypersensitivity reaction as cholestasis and / or liver problems, reducing the potency. Pharmacotherapeutic group: S01VS03 - antiarrhythmic and vertically The main pharmaco-therapeutic action: the antiarrhythmic action and has a moderate blocking effect on ?-adrenoreceptors, decreases the maximum rate of depolarization and action potential amplitude in purkinje fibers do not affect the resting potential, the most pronounced effect is registered in the system Hissa-purkinje; demonstrate the efficiency of organic heart lesions, including patients who have suffered MI. Method of production vertically drugs: Table., Coated tablets, 150 mg, 300 vertically Pharmacotherapeutic group: S07AV09 - selective antagonists of ?-blockers. Method of production of drugs: Mr injection, 10 mg / ml to 10 ml vial. The main pharmaco-therapeutic effects: anti arrhythmic effect, extending the third phase of action potential of cardiac cells is mainly due to slow flow in the potassium channel, causing bradykardychnyy effect by lowering sinus automatism, such action is not antagonistic to atropine, a noncompetitive ?-and ?-anti-adrenergic effect, slows conduction in the SA-node, atrial and AV-node, which is more pronounced when accelerating rhythm, intraventricular conduction does not change, increases refractory period and reduces the excitability of atrial myocardium, AV-node and ventricular levels, slows conduction and prolonged refractory period in additional AV-tract vertically reduces oxygen consumption by moderate decrease peripheral resistance and decrease heart rate, increases coronary blood flow by a direct effect on smooth muscle artery infarction and supports cardiac output vertically reducing the pressure and peripheral resistance, without revealing any negative inotropic effects vertically . Dosing and Administration of drugs: the recommended dose for adults - the therapeutic dose for patients weighing 70 kg, as typically is 450 - 600 mg / day (150 mg 3 g / day or 300 mg, 2 g / day) in some cases may require increase daily dose to 900 mg (300 mg 3 g / day) - MDD, patients with lower body weight to reduce the dose; increase the recommended dose gradually, at intervals of 3-4 days, the duration of treatment is determined by the clinical condition of the patient. states. Contraindications to the use of drugs: As soon as possible II and III. Contraindications to the use of drugs: hypersensitivity to the drug; AV block II - III degree, cardiogenic shock, Maximum Inspiratory Pressure hypotension, severe heart failure, sinus weakness, liver and kidney disease, pregnancy, lactation, infancy. Indications for use drugs: SUPRAVENTRICULAR tahiarytmiyi, including atrial fibrillation, atrial flutter; sinus tachycardia, tachycardia, hypertension, including during and after surgery, the rapid ventricular rate regulation in patients with atrial fibrillation or atrial flutter in the Angiotensin-Converting Enzyme before surgery, after surgery and other when you need a rapid ventricular rate regulation with short-acting drug, with uncompensated sinus tachycardia, in which a specific intervention is necessary for rapid vertically of heart rate, not intended for use in XP.
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